An IDRA-21 Experience and What’s Next

Since I got the flu and nothing better to do, it is the perfect time to experiment with some IDRA-21. What I failed to mentioned in my last post is that I have successfully weaned off of clonazepam. Not really. I just ran out and decided not to get a refill. Wasn’t as hard as I had read, but then again I did not use it for more than a month or two. It made me a very emotional person when under the effects. Did not like it.

1:10 PM – I take a tablet 10mg of IDRA-21.
2:40 PM – I take another 10mg of the ampakine drug, and 200mg of magnesium, in the form of diglycinate.

7:03 PM – I have a headache. Can’t say it’s from the ampakine. Might just be from the eyestrain of staring at the screen of my laptop. I will have to test further on another day.

The next day

That was a mighty fine headache I got yesterday. Luckily an OTC pain reliever was enough to rid me of it. I woke up feeling fine, but as the day progresses I get the same flu-type feelings as yesterday. It peaks at night and resets in the morning.

Current stack

I currently use the following substances in pursuit of increased work satisfaction and productivity.

  • Modafinil – 100mg in the morning, rarely 200mg when sleep deprived
  • Magnesium – 200mg to 400mg per day of magnesium diglycinate
  • Melatonin – 1mg before bed
  • Zinc – occasional 15mg zinc diglycinate tablet

Future stack

I have ordered the N-acetyl SEMAX amidate, N-Acetyl Selank and Noopept nasal sprays from Ceretropic. Hoping it will all go well, without the customs hassle ordering from US to EU.

Favorites so far

I have tried a considerable amount of substances that could classify as nootropics. I will try to list most of them and highlight my favourites or the one’s I would like to try again.

Tianeptine from eBay
Packaging of the Tianeptine I bought on eBay
  • Huperzine A 1% extract – enhanced visual memory, very noticeable, easy to overdose
  • Pramiracetam – emotionless, would like to try again
  • Noopept – focus, long-term memory
  • Piracetam – did not get any noticeable accute effects
  • Oxiracetam – did not get any noticeable accute effects
  • Armodafinil – holy cow! wide awake for too long, feel no need for sleep for a long amount of time at 75mg
  • Modafinil – just the right amount of wakefulness for the right amount of time at 100mg
  • IDRA-21 – did not get any noticeable accute effects
  • Sulbutiamine – did not get any noticeable acute effects
  • Ashwagandha – I find it made me feel more emotions, no effect on anxiety
  • 5-HTP – no noticeable acute effects, mydriasis
  • L-tyrosine – fast tolerance, subtle effects
  • Mucuna Pruriens – very slight euphoria, was not useful
  • Tianeptine –  the sodium form works well, euphoric

IDRA-21 Not for Me, Back on Modafinil

IDRA-21 disappoints

I am aware that a lot of time has passed since my last post, but I am back… again. I ended up receiving double the amount of IDRA-21 tablets. Yup. Either the nootropics store, Intellimeds, made a mistake and forgot about me or the original package got lost during transit. They made up for it.

IDRA-21 package
IDRA-21 packaging from Intellimeds

My thoughts on the substance so far are not very positive. The effects seem subtle, and not what I am looking for. I feel like it makes me more emotional. Each tablet supposedly contains 10mg of IDRA-21. I have not taken more than 20mg in a single dose. I am going to test it a bit more and go up to 30mg. If you have decided to try it as well, I would advise starting with a dosage as low as 5mg. Work your way up.

Modafinil is one of my pillars

Ordered a total of 100 tablets of 200mg Modalert. I work as a backend developer (PHP & MySQL) for a media agency and I find Modafinil a very useful tool. It helps me focus on a task for an extended amount of time. I

took it every day for a couple of weeks. I have been trying to take some days off now. I am not on Modafinil at the time of writing this post, because it is Saturday and I have managed to get the flu. Yeah, gotta rest and consume a lot of fluids, but I decided to update the blog for you anyway. Oh yeah, I take half a pill and very very rarely the whole 200mg.

Modalert I received from ModafinilBank
Modalert I received from ModafinilBank

If you managed to make it this far, then congratulations, and thank you for reading. I have no idea if anyone actually reads this because I have not gotten any feedback.

What else? I have been able to experiment with Tianeptine in the meantime. This was after I had received the benzothiadiazine-based IDRA. I found a vendor on eBay and took the plunge. I really liked Tianeptine Sodium, but the Sulfate version was a dud for me. I did not notice much from the Sulfate except slight feelings of discomfort. The Sodium, however, was awesome. You get this mild euphoria every time you dose. Pretty useful for social encounters. To keep it up you have to dose every 3-4 hours. The recommended dosage is 12.5mg, taken 3 times daily.

Selegiline and It’s Unexpected Arrival

Unexpected products

I did not expect to receive the Selegiline and Noopept before IDRA-21. But here they are, and with a couple of unexpected additions (thanks, Nootropics Mall!). They added in an extra sheet of Piracetam AL and Piracebral, both 800 mg. I tried one, along with a capsule of Noopept, last night since I have not noticed any sleep disturbances with them before.

Selegiline, Noopept and more

This morning I proceeded to take a single tablet of Piracetam and a 10 mg capsule of Noopept. About an hour after, I took this day’s Lumosity workout, as someone suggested on Google+ that I keep track of my cognitive function and its possible climb (or descent) on it. There was no effect that I was aware of, but here are my results.

Lumosity after Noopept
After Noopept & Piracetam
Lumosity before Noopept
Before Noopept & Piracetam

I refrained from taking Selegiline before finishing Lumosity as to not skewer the results. I took a pill of 5 mg Selegiline, broke it in four pieces and took about 1,25 mg sublingually. It did not take long, about 10 minutes, until I felt different. It is hard to label these effects as of now, but I will try nevertheless.

Initial effects of Selegiline

Effects that I have noticed upon two days of dosing. Someone noted that the cognitive effects develop fully by 2 weeks.

Selegiline tablet Jumex

October 7 – The first day I took 1,25 mg, sublingually, in the morning and the afternoon and 2,5 mg orally. That’s a total of 5 milligrams. First sublingual dose of the day definitely had a noticeable effect.

October 8  – Today, I started with 2,5 mg sublingually and 5 mg orally with food and fish oil. Selegiline is fat soluble and taking it with fatty food increases oral bioavailability. Also ate two handfuls of cocoa nibs and took a few drops of Rhodiola rosea extract.

  • strange feeling of slight stimulation (?) / very slight euphoria (?), mood boost
  • time speeds up / you get focused / lose yourself
  • enhanced music appreciation

Where Are You, IDRA-21?

There is no sign of IDRA-21 as of yet, I’m afraid. It shipped 6 days before the Selegiline and Noopept, from a closer country. This could be a problem of either the site I ordered it from, its country’s postal service or my country’s customs.

I will keep you posted.

IDRA-21 Reversing Memory Deficits

IDRA-21

I recently stumbled upon a new and exotic nootropic belonging to the ampakine class – IDRA-21. Of course, me being impulsive as usual, rushed into ordering 40 tablets of it for myself. Costly. To be honest, I did do some research beforehand.

Fight against alprazolam with IDRA-21?
Alprazolam (commonly known as Xanax)

There have been no clinical trials on humans but it shows nootropic effects in animals by appreciably improving learning and memory and reversing cognitive deficits induced by a drug (alprazolam – commonly known as Xanax) used for treating anxiety and panic attacks.

Studies on monkeys show that IDRA-21 is about 10-fold more potent than aniracetam in reversing learning deficits induced by alprazolam. This interests me because I use both alprazolam and clonazepam every once in a while. Not very smart of me, I know.

Purported effects of IDRA-21

  • improves learning and memory
  • reverses cognitive deficits caused by alprazolam
  • effects lasting up to 48 hours
  • exacerbates excitotoxicity during stroke

What I want to reach

Most supplements, especially the bioavailable forms and newer nootropics, cost a considerable amount of money. This is why my stack is so empty and basic. Now that I am going to study software development at school, I am looking to add and refine my stack.

The effects I am aiming for are the following:

  • improved focus (thinking Noopept)
  • improved memory (IDRA-21?)
  • improved self-control (something dopaminergic?)
  • improved wakefulness (Rhodiola rosea?)
  • reduced anxiety (clonazepam)

The lonely stack I have now

  • magnesium diglycinate (400 – 600mg per day)
  • zinc diglycinate (15 – 30mg per day)
  • vitamin C (500mg every other day)
  • a low quality fish oil with vitamin D, A and E

I am looking to replace the fish oil with a higher quality one I found that gives a dose of 600mg of EPA/DHA per serving. I will let you know once I receive the IDRA-21 and how it affects me, keeping a more detailed and less frantic log than I did with my earlier self-experiments.